Smitha recently presented a great case of what at first looked like Guillain-Barré syndrome but turned out to be CIDP. There was some discussion of AIDP vs. SIDP vs. CIDP.
I’ve been reading the recent Continuum on peripheral neuropathy and came across a term I hadn’t heard before: Acute-onset CIDP, or A-CIDP. They applied this term to patients who reach plateau within 4 weeks, but then relapse more than once or continue to progress or require maintenance immunomodulatory therapy.
The Continuum article referenced a paper that looked at the differences between AIDP and A-CIDP. The bottom line was that sensory abnormalities were more common in the latter, whereas electrophysiology didn’t distinguish them.
The paper didn’t address the question of whether A-CIDP was particularly likely to be associated with an underlying systemic pathology. Perhaps we can get some input on that from our neuromuscular colleagues.
What? You thought all we’re going to talk about is stroke? This is a full-service residency blog!