Tag Archives: Evidence-Based Medicine

Team Endovascular Extends Winning Streak to 4

Lots of exciting news coming from Nashville, as expected. In addition to MR CLEAN, we now have positive results from ESCAPE, EXTEND-IA, and SWIFT PRIME. I thought it might be useful to line up the key clinical and radiographic inclusion … Continue reading

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Endovascular Breakthrough*

By now, most interested people are well-aware of the MR CLEAN results; if not, you can read the article here. Following are just a few thoughts and observations: One thing that caught my eye is that the absolute difference between endovascular therapy and conservative … Continue reading

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Mechanical Heart Valves: Dual Antithrombotic Therapy?

The question came up at stroke conference today, and here’s a link to the American College of Chest Physicians guideline that addresses the issue. On the basis of a meta-analysis of relatively low-quality research reports, they recommend, for patients at low … Continue reading

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Risk vs. Uncertainty

  I’ve got another excellent book recommendation: Risk Savvy: How to Make Good Decisions, by Gerd Gigerenzer. Prof. Gigerenzer directs the Max Plank Center for Human Development in Berlin, and has had a long and illustrious academic career. His current focus is on … Continue reading

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New Statistics Resource

Via The Incidental Economist, I learned that JAMA is rolling out a new feature–a guide to statistics and methods. The neat thing about they way they’ve organized this is that each article will discuss a statistical method actually employed in … Continue reading

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Annals of “Things we thought were beneficial but might not be”

We can add therapeutic hypothermia after cardiac arrest to the list. A recent study randomized post-arrest subjects to target temperatures of 36 °C versus 33 °C and found no difference in neurologic outcome. As discussed in the article and in this pithy editorial, it … Continue reading

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Annals of “Things we thought were beneficial but might not be”

Custom-made infant helmets as a remedy for skull flattening (picture at left from a New York Times article on the subject).

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Updated Stroke Prevention Guidelines

The 2014 update to the American Heart Association’s “Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack” is available here. These guideline documents are very long and detailed, which is good when you want to delve … Continue reading

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Rehabilitation Measures Database

I came across a good website today, produced by the Rehab Institute of Chicago, et al. It’s a rehabilitation measures database, containing descriptions of hundreds of instruments used in research studies and clinical practice. Each entry has a description of the … Continue reading

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Applying Bayes’s Theorem*

Our curriculum is supposed to include formal training in evidence-based medicine. I think we discuss these methods a lot, but we don’t have a whole module on it the way some large residencies do; there is an evidence-based medicine tag … Continue reading

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