Tag Archives: Stroke

Team Endovascular Extends Winning Streak to 4

Lots of exciting news coming from Nashville, as expected. In addition to MR CLEAN, we now have positive results from ESCAPE, EXTEND-IA, and SWIFT PRIME. I thought it might be useful to line up the key clinical and radiographic inclusion … Continue reading

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Endovascular Breakthrough*

By now, most interested people are well-aware of the MR CLEAN results; if not, you can read the article here. Following are just a few thoughts and observations: One thing that caught my eye is that the absolute difference between endovascular therapy and conservative … Continue reading

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The Perils of Venture Capital Funding for Clinical Research

When I was a stroke fellow, UCSD was the coordinating center for a multicenter trial of a promising device called NeuroThera, made by a local company called PhotoThera. NeuroThera was kind of like an ultrasound machine, except that instead of insonating … Continue reading

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Mechanical Heart Valves: Dual Antithrombotic Therapy?

The question came up at stroke conference today, and here’s a link to the American College of Chest Physicians guideline that addresses the issue. On the basis of a meta-analysis of relatively low-quality research reports, they recommend, for patients at low … Continue reading

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Updated Stroke Prevention Guidelines

The 2014 update to the American Heart Association’s “Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack” is available here. These guideline documents are very long and detailed, which is good when you want to delve … Continue reading

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The Experience vs. the Explanation of Neurological Disease

  At the conclusion of stroke conference today, we watched a TED talk by Jill Bolte Taylor, the Harvard neuroanatomist who suffered a left hemispheric hemorrhage due to AVM rupture. She’s written a popular book about her experience of neurological deficit … Continue reading

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A Home-Grown Stroke Application

I just learned that our own Ahsan Sattar has helped develop an iOS application for cerebrovascular disease–think MDCalc for stroke and neurointervention. He’s looking for feedback and I already provided some about the TICI scale. I thought I’d put it out … Continue reading

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Dystextia

Check this out, via The Incidental Economist.

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Doing More, or Gizmo Idolatry

Writes a longtime friend and colleague (some details changed for privacy): 43yo man with right MCA stroke, found to have right ICA extracranial dissection with possible pseudoaneurysm right below petrous portion. Given the stroke, I put him on Coumadin and … Continue reading

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Blunt Cerebrovascular Trauma: Anticoagulation or Antiplatelet Therapy?

Thanks to Li for sending out a nice summary of this subject with excerpts from the relevant UpToDate article. The bottom line is that they acknowledge the lack of prospective data on this problem, but do recommend anticoagulation for grade … Continue reading

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